By Trygve O. Tollefsbol (auth.), Trygve O. Tollefsbol (eds.)
Biological getting older: tools and Protocols investigates many of the techniques which are plagued by the age of an organism. a number of new instruments for the research of organic getting older were brought lately, and this quantity presents tools and protocols for those new innovations as well as its assurance of demonstrated tactics. The editors have conscientiously chosen in simple terms these issues which are thought of mainstays of the sector or are displaying promise in revolutionizing this quite new technology. the 3 major parts of concentration during this state of the art compendium of organic getting older learn are: tools which are easy to realizing the basic mechanisms of mobile getting older; thoughts used to interfere within the getting older procedure; and methods to examining the numerous molecular approaches of organic getting older. Researchers looking new expertise and methods will locate this quantity of great gain as they stream in the direction of new instructions within the fascinating and increasing box of organic getting older.
Read or Download Biological Aging: Methods and Protocols PDF
Best biology books
Cryptosporidium, in its quite a few varieties, is a widely known reason for outbreaks of waterborne sickness. Regulatory our bodies around the globe are more and more requiring the advance of "fit-for-purpose" detection equipment for this protozoan parasite, yet research is frequently problematical. Bringing jointly foreign educational and industry-based specialists, this ebook offers a finished overview of the present country of analytical recommendations for the detection of cryptosporidium, in addition to most likely destiny advancements.
This quantity is the 3rd in a chain on depressive affliction. the 1st quantity, entitled Phenomenology of Depressive ailment, is dedicated to a de scription of depressive ailment from quite a few views that come with these of the sufferer, the clinician, and the psychiatric researcher. It de scribes the foremost subtypes of depressive sickness and locations them within the context of the lifestyles cycle.
Because the prior rotifer symposia in Lunz and Gent have been hugely profitable, it used to be thought of vital to proceed the culture each 3rd yr. therefore a 3rd rotifer symposium used to be held in Uppsala, Sweden, Aug. 30-Sept. four, 1982. at the start of 1981 the 1st round used to be mailed to the members of the former symposia, who in flip have been asked to indicate names of alternative scientists to be invited.
Chemokines play an enormous function in recruiting inflammatory cells into tissues in line with an infection and irritation. in addition they play an enormous position in coordinating the stream of T-cells, B-cells and dentritic cells, essential to generate an immune reaction (response to damage, allergens, antigens, invading microorganisms).
- Biology of Growth Factors: Molecular Biology, Oncogenes, Signal Transduction, and Clinical Implications
- International Review of Cytology, Vol. 29
- Advances in Enzymology and Related Areas of Molecular Biology: And Related Areas of Molecular Biology, Volume 76
- Infested: How the Bed Bug Infiltrated Our Bedrooms and Took Over the World
- Systems Metabolic Engineering: Methods and Protocols
Additional resources for Biological Aging: Methods and Protocols
J. (1993) Replicative senescence of human fibroblast-like cells in culture. Physiological Reviews 73, 617–638. 22. Cristofalo, V. J. (1988) Cellular biomarkers of aging. Exp. Gerontol. 23, 297–307. 23. , et al. (1993) Failure of senescent human fibroblasts to express the insulin-like growth factor-1 gene. J. Biol. Chem. 265, 17,883–17,888. 24. , Phillips, P. , Knowles, B. , and Cristofalo, V. J. (1994) Cleavage of the epidermal growth factor receptor by a membrane-bound leupeptin-sensitive protease active in nonionic detergent lysates of senescent but not young human diploid fibroblasts.
Cell 120, 557–567. 4. Macieira-Coelho, A. (1988) Behavior of cells in culture and physiopathology of organism, in Biology of Normal Proliferating Cells in vitro. Relevance for in vivo Aging (von Hahn, H. ). Karger, Basel, Switzerland: pp 6–20. 5. Rubin, H. (1966) A substance in conditioned medium which enhances the growth of chick embryo cells in tissue culture. Exp. Cell Res. 41, 138–148. 6. Macieira-Coelho, A. (2000) Ups and downs of aging studies in vitro: The crooked path of science. Gerontol.
And Lotze, C. (1995) Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence? Exp. Cell Res. 220, 186–193. 21. Chen, Q. , Bartholomew, J. , Reagan, J. , and Ames, B. N. (1998) Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication. Biochem. J. 332( Pt 1), 43–50. 22. , de Oliveira, R. , Conboy, C. , and Guarente, L. (2003) Superoxide dismutase 1 knock-down induces senescence in human fibroblasts.