By Trygve O. Tollefsbol (auth.), Trygve O. Tollefsbol (eds.)

Biological getting older: tools and Protocols investigates many of the techniques which are plagued by the age of an organism. a number of new instruments for the research of organic getting older were brought lately, and this quantity presents tools and protocols for those new innovations as well as its assurance of demonstrated tactics. The editors have conscientiously chosen in simple terms these issues which are thought of mainstays of the sector or are displaying promise in revolutionizing this quite new technology. the 3 major parts of concentration during this state of the art compendium of organic getting older learn are: tools which are easy to realizing the basic mechanisms of mobile getting older; thoughts used to interfere within the getting older procedure; and methods to examining the numerous molecular approaches of organic getting older. Researchers looking new expertise and methods will locate this quantity of great gain as they stream in the direction of new instructions within the fascinating and increasing box of organic getting older.

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And Lotze, C. (1995) Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence? Exp. Cell Res. 220, 186–193. 21. Chen, Q. , Bartholomew, J. , Reagan, J. , and Ames, B. N. (1998) Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replication. Biochem. J. 332( Pt 1), 43–50. 22. , de Oliveira, R. , Conboy, C. , and Guarente, L. (2003) Superoxide dismutase 1 knock-down induces senescence in human fibroblasts.

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